Miloš Svirčev

Miloš Svirčev, PhD

Assistant Professor

Chair of Biochemistry and Chemistry of Natural Products

CONTACT

University of Novi Sad Faculty of Sciences

Department of Chemistry, Biochemistry and Environmental Protection

Office 10/III

Trg Dositeja Obradovića 3

21000 Novi Sad, Serbia

Tel: + 381 21 485 2768

e-mail: milos.svircev@dh.uns.ac.rs

SCOPUS Author ID: 13003366200

ORCID: https://orcid.org/0000-0003-1808-1315

EDUCATION

  • 2018. PhD in Biochemistry, University of Novi Sad Faculty of Sciences, Serbia
  • 2009. Magister in Chemistry, University of Novi Sad Faculty of Sciences, Serbia
  • 2004. BSc in Chemistry, University of Novi Sad Faculty of Sciences, Serbia

SCIENTIFIC AND ACADEMIC POSITIONS

  • 2019-today Assistant Professor, University of Novi Sad Faculty of Sciences, Serbia
  • 2013-2019 Teaching Assistant, University of Novi Sad Faculty of Sciences, Serbia
  • 2009-2013 Research Assistant, University of Novi Sad Faculty of Sciences, Serbia
  • 2005-2009 Junior Researcher, University of Novi Sad Faculty of Sciences, Serbia.

TEACHING

  • Enzymology
  • Rational drug design
  • Bioinformatics
  • Chemoinformatics
  • Importance of Biochemistry in Modern Society

TEXTBOOKS

  • Popsavin, M., Vukojević, N., Hranisavljević, J., Kovačević, I., Srećo Zelenović, B., Svirčev, M. Practicum in Chemistry of Natural Products, (in Serbian), University of Novi Sad Faculty of Sciences, Novi Sad, Serbia.

RESEARCH FIELDS

  • Design, development and synthesis of novel biologically active compounds
  • Medicinal chemistry.

SELECTED PROJECTS

  • Synthesis and biological testing of new mimics or derivatives of selected cytotoxic lactones, antitumor agent tiazofurin and natural naphthenic acids, Ministry of Education, Science and Technological Development of the Republic of Serbia (2011-2019)
  • Synthesis and biomedicinal testings of anticancer agents derived from naturally available monosaccharides, Provincial Secretariat for Science and Technological Development, Autonomous Province of Vojvodina, Serbia (2012-2013).
  • Synthesis of selected biologically active molecules and analogues of potential interest in biomedicine and agronomy, Ministry of Education, Science and Technological Development of the Republic of Serbia (2006-2010).

SELECTED PUBLICATIONS

  1. Svirčev, M., Popsavin, M., Pavić, A., Vasiljević, B., Rodić, M. V., Djokić, S., Kesić, J., Srećo Zelenović, B., Popsavin, V., Kojić, V. (2022): Design, synthesis, and biological evaluation of thiazole bioisosteres of goniofufurone through in vitro antiproliferative activity and in vivo toxicity. Bioorganic Chemistry. 121: 105691.
  2. Svirčev, M., Benedeković, G., Kovačević, I., Popsavin, M., Kojić, V., Jakimov, D., Srdić-Rajić, T., Rodić, M. V., Popsavin, V. (2018): Conformationally restricted goniofufurone mimics with halogen, azido or benzoyloxy groups at the C-7 position: Design, synthesis and antiproliferative activity. Tetrahedron. 74: 4761–4768.
  3. Popsavin, M., Kojić, V., Torović, Lj., Svirčev, M., Spaić, S., Jakimov, D., Aleksić, L., Bogdanović, G., Popsavin, V. (2016): Synthesis and in vitro antitumour activity of tiazofurin analogues with nitrogen functionalities at the C-2′ position. European Journal of Medicinal Chemistry. 111: 114–125.
  4. Popsavin, M., Kojić, V., Spaić, S., Svirčev, M., Bogdanović, G., Jakimov, D., Aleksić, L., Popsavin, V. (2014): 2-Substituted thiazole-4-carboxamide derivatives as tiazofurin mimics: Synthesis and in vitro antitumour activity. Tetrahedron. 70: 2343–2350.
  5. Popsavin, M., Spaić, S., Svirčev, M., Kojić, V., Bogdanović, G., Popsavin, V. (2012): Synthesis and in vitro antitumour screening of 2-(β-D-xylofuranosyl)thiazole-4-carboxamide and two novel tiazofurin analogues with substituted tetrahydrofurodioxol moiety as a sugar mimic. Bioorganic & Medicinal Chemistry Letter. 22: 6700–6704.

additional information

  • Member of Serbian Chemical Society.