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Faculty of Sciences, University of Novi Sad

Department of Chemistry, Biochemistry and Environmental Protection

+381-21-485-2720 infohemija@dh.uns.ac.rs

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dr Ljubica Grbovic

Ljubica Grbović, PhD

Full Professor

Chair of Organic Chemistry

CONTACT

University of Novi Sad Faculty of Sciences

Department of Chemistry, Biochemistry and Environmental Protection

Office: 19/III

Adress: Trg Dositeja Obradovića 3

21000 Novi Sad, Serbia

Tel:+ 381 21 485 2760

e-mail: ljubica.grbovic@dh.uns.ac.rs

SCOPUS Author ID: 15769018400

EDUCATION

  • 2009. PhD in Chemistry, Faculty of Sciences University of Novi Sad, Serbia
  • 1999. MSc in Chemistry, Faculty of Sciences University of Novi Sad, Serbia
  • 1992. BSc in Chemistry, Faculty of Sciences University of Novi Sad, Serbia

SCIENTIFIC AND ACADEMIC POSITIONS

  • 2026. Full professor, Faculty of Sciences University of Novi Sad, Serbia
  • 2016-2026. Associate professor, Faculty of Sciences University of Novi Sad, Serbia
  • 2011-2016. Assistant professor, Faculty of Sciences University of Novi Sad, Serbia
  • 1995-2011. Teaching Assistant, Faculty of Sciences University of Novi Sad, Serbia
  • 1994-1995. Research Assistant, Faculty of Sciences University of Novi Sad, Serbia

TEACHING

  • Organic Chemistry II
  • Preparativ Organic Chemistry
  • Microwaves in Green Chemistry
  • Chemistry of Oil
  • Chemistry of Free Radicals  
  • Mechnanisms of Organic Reactions
  • Selected Chapters in Organic Chemistry
  • Synthetic drugs and precursors (Master Academic Forensic Studies, Center for Multidisciplinary Forensic Studies “Dr Archiebald Rice”).

TEXTBOOKS

  • Grbović, Lj., Pavlović, K., Vasiljević, B., Microwaves in Green Organic Chemistry, Faculty of Sciences University of Novi Sad, 2020.
  • Grbović, Lj., Ajduković, J., Nikolić, A., Savić, M., Pavlović, K., Oklješa, A., Bjedov, S., Organic Chemistry – Practical Textbook, Faculty of Sciences University of Novi Sad, 2019.
  • Sakač, M., Grbović, Lj. Preparativ Organic Chemistry – Practical Textbook, Faculty of Sciences University of Novi Sad, 2015.

RESEARCH FIELDS

  • Organic synthesis
  • Chemical transformations of naphthenic acids, bile acids and carbohydrates
  • Microwave-assisted synthesis of biologically active molecules

SELECTED PROJECTS

  • A New Screening Method for Application in Directed Evolution of Human Steroid Metabolizing Enzymes, International Bilateral Project(2022-2024).
  • Regulation of metabolism of endogenous steroids by inhibitors of cytochrome P450-dependent monooxygenases: molecular and cell mechanisms, Bilateral project (2020-2021).
  • Program of scientific research work of NIO, Ministry of Education, Science and Technological Development of the Republic of Serbia (2020-).
  • New extraction procedures in methods for determining the total antioxidant capacity as well as toxic substances in fruits and foods of plant origin, International Bilateral Project (2016-2017).
  • Synthesis and biological testing of new mimics or derivatives of selected cytotoxic lactones, antitumor agent tiazofurin and natural naphthenic acids, Ministry of Education, Science and Technological Development of the Republic of Serbia (2011-2019).
  • Synthesis of selected biologically active molecules and analogues of potential interest for biomedicine and agronomy, Ministry of Education, Science and Technological Development of the Republic of Serbia (2006-2010).

SELECTED PUBLICATIONS

  1. Dzichenka, Y., Shapira, M., Sachanka, A., Cherkesova, T., Shchur, V., Grbović,, Pavlović, K., Vasiljević, B., Savić, M., Nikolić, A., Oklješa, A., Ajduković, J., Kuzminac, I., Yantsevich, A., Usanov, S., Jovanović-Šanta, S. (2025): Discovery of the potential of cholesterol-lowering human CYP7 enzymes as biocatalysts for the production of C7 hydroxylated steroids, Biophysical Chemistry, 319, 107393. doi: 10.1016/j.bpc.2025.107393
  2. Pavlović, K., Grbović, Lj., Karadžić Banjac, M., Kovačević, S., Mandić, A., Podunavac-Kuzmanović, S., Vasiljević, B. (2023): Microwave Synthesis of Novel Chenodeoxycholic Acid Esters and Comparative Study of Chromatographic Behavior and Lipophilicity, Macedonian Journal of Chemistry and Chemical Engineering, 42, 165-174. doi: 20450/mjcce.2023.2707
  3. Ilić, M., Pastor, K., Marković, J., Grbović, Lj., Jovanović-Šanta, S., Mitrović, I., Trivunović, Z., Ačanski, M. (2022): Feasibility study of separation and purification of bile acid derivatives by HPLC on C18 and F5 columns. Steroids. 186. doi: 10.1016/j.steroids.2022.109074
  4. Marinović, M., Petri, E., Grbović, Lj., Vasiljević, B., Jovanović-Šanta, S., Bekić, S., Ćelić, A. (2022): Investigation of the potential of bile acid methyl esters as inhibitors of aldo-keto reductase 1C2: insight from molecular docking, virtual screening, experimental assays and molecular dynamics Molecular Informatics. 41. doi: 10.1002/minf.202100256
  5. Dzichenka, Y., Shapira, M., Yantsevich, A., Cherkesova, T., Grbović, Lj., Savić, M., Usanov, S., Jovanović-Šanta, S. (2020): Modified bile acids and androstanes – Novel promising inhibitors of human cytochrome P450 17A1. Journal of Steroid Biochemistry and Molecular Biology. 205. doi: 10.1016/j.jsbmb.2020.105777